Wntepane 1 |CAS:1314885-81-8 Probechem Biochemicals

Chemical Structure : Wntepane 1

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Wntepane 1

货号: PC-62039Not For Human Use, Lab Use Only.

Wntepane 1 is a small-molecule activator of the Wnt pathway that modulates the van-Gogh-like receptor 1 (Vangl1), activates Wnt signaling with EC50 of 1.8 uM in the reporter gene assay.

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生物&药学活性

Wntepane 1 is a small-molecule activator of the Wnt pathway that modulates the van-Gogh-like receptor 1 (Vangl1), activates Wnt signaling with EC50 of 1.8 uM in the reporter gene assay.
Wntepane 1 interacts with Vangl1 (and possibly Vangl2 as well) and thereby at least partially liberates and restores the signal transducing activity of Dsh.
Wntepane 1 is an advantageous tool for the study of biological processes mediated by Vangl1.

物理化学性质&存储条件

分子量	474.557
分子式	C28H30N2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3aR,9R,10aR,10bS)-6,6-dimethyl-1,3-dioxo-2-phenyl-2,3,3a,4,6,8,9,10,10a,10b-decahydro-1H-oxepino[4,3-e]isoindol-9-yl benzylcarbamate

参考文献

1. Basu S, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6805-10.

Wntepane 1

生物&药学活性

物理化学性质&存储条件

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Wntepane 1

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