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Werner syndrome RecQ helicase-IN-4

Chemical Structure : Werner syndrome RecQ helicase-IN-4

CAS No.: 2869954-53-8

Werner syndrome RecQ helicase-IN-4

货号: PC-20677Not For Human Use, Lab Use Only.

Werner syndrome RecQ helicase-IN-4 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 60 nM for WRN ATPase.

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5 mg ¥3980 In stock
10 mg ¥5980 In stock
25 mg ¥8980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Werner syndrome RecQ helicase-IN-4 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 60 nM for WRN ATPase.

物理化学性质&存储条件

分子量 666.65
分子式 C32H33F3N8O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(3-hydroxypicolinoyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)-N-(2-methyl-4-(trifluoromethyl)phenyl)acetamide

参考文献

1. Patent WO2022249060A1.

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