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Wee1 Inhibitor II

Chemical Structure : Wee1 Inhibitor II

CAS No.: 622855-50-9

Wee1 Inhibitor II

货号: PC-72319Not For Human Use, Lab Use Only.

Wee1 Inhibitor II is a potent, selective, ATP-binding site-targeting inhibitor of Wee1 with IC50 of 59 nM, 590-fold selectivity over the related checkpoint kinase Chk1 (IC50=35 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Wee1 Inhibitor II is a potent, selective, ATP-binding site-targeting inhibitor of Wee1 with IC50 of 59 nM, 590-fold selectivity over the related checkpoint kinase Chk1 (IC50=35 uM).

    物理化学性质&存储条件

    分子量 418.877
    分子式 C24H19ClN2O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    Chemical Name/SMILES

    6-Butyl-4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3-(2H,6H)-dione

    参考文献

    1. Palmer, B.D., et al. 2006. J. Med. Chem. 49: 4896-4911.

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