WYE-28 | mTOR inhibitor | Probechem Biochemicals

Chemical Structure : WYE-28

CAS No.: 1062172-60-4

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货号: PC-27225Not For Human Use, Lab Use Only.

WYE-28 is a potent, selective and ATP-competitive inhibitor of mTOR with IC50 of 0.08 nM, inhibits PI3Kα with IC50 of 6 nM.

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WYE-28 is a potent, selective and ATP-competitive inhibitor of mTOR with IC50 of 0.08 nM, inhibits PI3Kα with IC50 of 6 nM.

分子量	586.65
分子式	C30H34N8O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl 4-(6-(4-(3-(4-(hydroxymethyl)phenyl)ureido)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate

1. Zask A, et al. J Med Chem. 2009 Aug 27;52(16):5013-6.