WXSH0208

Chemical Structure : WXSH0208

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货号: PC-27363Not For Human Use, Lab Use Only.

WXSH0208 is a baloxavir marboxil derivative and selective inhibitor of influenza RNA polymerase subunit, inhibits cap-dependent endonuclease (CEN), shows antiviral activity against influenza A and B viruses in vitro, including strains resistant to baloxavir, also inhibits Crimean-Congo haemorrhagic fever virus (CCHFV) endonuclease activity and suppresses viral replication with EC50 of 4.2 uM.

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25 mg		Get quote
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100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	439.42
分子式	C23H19F2N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(7aS,16R)-2,3-difluoro-10-hydroxy-8-methyl-16-phenyl-6,7,7a,8-tetrahydro-16H-benzo[b]pyrido[1',2':1,6][1,2,4]triazino[2,3-e][1,5]oxazocine-9,11-dione

参考文献

1. Feng, J. et al. J. Med. Chem. 67, 2570–2583 (2024).

2. Cao W, et al. J Infect Dis. 2025 Aug 14;232(2):441-449.

3. Xue L, et al. Nature. 2026 Jul 22. doi: 10.1038/s41586-026-10701-6.

WXSH0208

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物理化学性质&存储条件

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WXSH0208

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