WS3 | β cells proliferation inducer | Probechem Biochemicals

Chemical Structure : WS3

CAS No.: 1421227-52-2

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WS3 (β cells proliferation inducer)

货号: PC-43044Not For Human Use, Lab Use Only.

WS3 is a small molecule that can induce proliferation of β cells with EC50 of 74 nM, modulates the activity of Erb3 binding protein-1 and the IκB kinase pathway.

规格	价格	库存
10 mg	￥780	In stock
25 mg	￥1180	In stock
50 mg	￥1980	In stock
100 mg		Get quote

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生物&药学活性

WS3 is a small molecule that can induce proliferation of β cells with EC50 of 74 nM, modulates the activity of Erb3 binding protein-1 and the IκB kinase pathway.
WS3 can reversibly proliferates primary RPE cells isolated from fetal and adult human donors.

物理化学性质&存储条件

分子量	569.5781
分子式	C28H30F3N7O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	DMSO: ≥ 43 mg/mL
Chemical Name/SMILES	Cyclopropanecarboxamide, N-[6-[4-[[[[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-4-pyrimidinyl]-

参考文献

1. Swoboda JG, et al. ACS Chem Biol. 2013 Jul 19;8(7):1407-11.

2. Shen W, et al. J Am Chem Soc. 2013 Feb 6; 135(5):1669-72.

WS3 (β cells proliferation inducer)

生物&药学活性

物理化学性质&存储条件

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WS3 (β cells proliferation inducer)

生物&药学活性

物理化学性质&存储条件

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