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WNK inhibitor 7

Chemical Structure : WNK inhibitor 7

CAS No.: 2125724-72-1

WNK inhibitor 7 (WNK-IN-7)

货号: PC-61065Not For Human Use, Lab Use Only.

WNK inhibitor 7 (WNK-IN-7) is a potent, selectiive inhibitor of WNK1 kinase with IC50 of 95 nM, shows IC50 of 1.39 uM in the cellular OSR1 phosphorylation assay with reasonable aqueous solubility.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    WNK inhibitor 7 (WNK-IN-7) is a potent, selectiive inhibitor of WNK1 kinase with IC50 of 95 nM, shows IC50 of 1.39 uM in the cellular OSR1 phosphorylation assay with reasonable aqueous solubility.

    物理化学性质&存储条件

    分子量 399.538
    分子式 C26H29N3O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-((1-(2-(3-methoxyphenyl)-5-methylpyridin-4-yl)-1H-indol-3-yl)methyl)-2-methylpropan-1-amine

    参考文献

    1. Yamada K, et al. ACS Chem Biol. 2016 Dec 16;11(12):3338-3346.

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