WK-298 |CAS:1067654-70-9 Probechem Biochemicals

Chemical Structure : WK-298

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WK-298 (WK298;WK 298;Novartis 101)

货号: PC-60436Not For Human Use, Lab Use Only.

WK-298 (Novartis 101) is a potent small molecule inhibitor that binds and disrupts the MDM2/MDMX-p53 interaction with IC50 of 0.19 uM and 19.7 uM, respectively.

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生物&药学活性

WK-298 (Novartis 101) is a potent small molecule inhibitor that binds and disrupts the MDM2/MDMX-p53 interaction with IC50 of 0.19 uM and 19.7 uM, respectively.

物理化学性质&存储条件

分子量	629.63
分子式	C35H38Cl2N6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-(6-chloro-3-(1-(4-chlorobenzyl)-4-phenyl-1H-imidazol-5-yl)-1H-indol-2-yl)(3-((3-(dimethylamino)propyl)(methyl)amino)pyrrolidin-1-yl)methanone

参考文献

1. Popowicz GM, et al. Cell Cycle. 2010 Mar 15;9(6):1104-11.

2. Lemos A, et al. Med Res Rev. 2016 Sep;36(5):789-844.

WK-298 (WK298;WK 298;Novartis 101)

生物&药学活性

物理化学性质&存储条件

参考文献

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WK-298 (WK298;WK 298;Novartis 101)

生物&药学活性

物理化学性质&存储条件

参考文献

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