WEE1Hu inhibitor 1 |CAS:2211167-11-0 Probechem Biochemicals

Chemical Structure : WEE1Hu inhibitor 1

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WEE1Hu inhibitor 1 (Wee1A inhibitor 1)

货号: PC-35251Not For Human Use, Lab Use Only.

WEE1Hu inhibitor is a novel potent inhibitor of WEE1Hu kinase (also known as Wee1A) with IC50 of 68 nM against recombined WEE1Hu in ELISA assays.

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生物&药学活性

WEE1Hu inhibitor 1 is a novel potent inhibitor of WEE1Hu kinase (also known as Wee1A) with IC50 of 68 nM against recombined WEE1Hu in ELISA assays.
WEE1Hu inhibitor 1 inhibits lung cancer cell Hep-3B and Huh-7 cell proliferation with IC50 of <1 uM and 10-100 uM, respectively.

物理化学性质&存储条件

分子量	461.311
分子式	C18H20IN7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(1H-imidazol-1-yl)-5-iodo-N-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine

参考文献

1. US Patent WO 2018056621.

WEE1Hu inhibitor 1 (Wee1A inhibitor 1)

生物&药学活性

物理化学性质&存储条件

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WEE1Hu inhibitor 1 (Wee1A inhibitor 1)

生物&药学活性

物理化学性质&存储条件

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