WDR5 WBM site inhibitor 7k

Chemical Structure : WDR5 WBM site inhibitor 7k

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货号: PC-21832Not For Human Use, Lab Use Only.

WDR5 WBM site inhibitor 7k is a selective small molecule inhibitor of WDR5 WBM binding site with Ki of 107 nM, inhibits lncRNA-WDR5 complex formation.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

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生物&药学活性

WDR5 WBM site inhibitor 7k is a selective small molecule inhibitor of WDR5 WBM binding site with Ki of 107 nM, inhibits lncRNA-WDR5 complex formation.
WDR5 WBM site inhibitor 7k shows no activity against WDR5 WIN site binding.
WDR5 WBM site inhibitor 7k reduces cMYC enrichment in WDR5 pull-down experiments, downregulates HOTTIP.

物理化学性质&存储条件

分子量	514.78
分子式	C19H17BrClN3O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((5-bromo-3-chloro-2-hydroxyphenyl)sulfonamido)-5-(1-cyanocyclobutyl)-2-hydroxy-N-methylbenzamide

参考文献

1. Chang JY, et al. RSC Med Chem. 2024 Jan 10;15(2):636-640.