WAY-196025 |CAS:540523-42-0 Probechem Biochemicals

Chemical Structure : WAY-196025

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WAY-196025 (WAY196025)

货号: PC-61842Not For Human Use, Lab Use Only.

WAY-196025 is a potent, selective, and orally active inhibitor of cPLA2α with IC50 of 12 nM for LTB4 inhibition.

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生物&药学活性

WAY-196025 is a potent, selective, and orally active inhibitor of cPLA2α with IC50 of 12 nM for LTB4 inhibition.
WAY-196025 shows efficacy in multiple acute and chronic prostaglandin and leukotriene dependent in vivo models.

物理化学性质&存储条件

分子量	746.14
分子式	C40H35Cl3N2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3-(1-benzhydryl-5-chloro-2-(2-(((3,4-dichlorophenyl)methyl)sulfonamido)ethyl)-1H-indol-3-yl)propyl)benzoic acid

参考文献

1. McKew JC, et al. J Med Chem. 2008 Jun 26;51(12):3388-413.

2. Whalen KA, et al. Clin Exp Allergy. 2008 Oct;38(10):1590-605.

3. Marusic S, et al. J Neuroimmunol. 2008 Nov 15;204(1-2):29-37.

WAY-196025 (WAY196025)

生物&药学活性

物理化学性质&存储条件

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WAY-196025 (WAY196025)

生物&药学活性

物理化学性质&存储条件

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