Vutiglabridin | Insulin sensitizer | Probechem Biochemicals

Chemical Structure : Vutiglabridin

CAS No.: 1800188-47-9

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Vutiglabridin (HSG4112)

货号: PC-73455Not For Human Use, Lab Use Only.

Vutiglabridin (HSG4112) is a synthetic structural analog of glabridin and insulin sensitizer, novel anti-obesity agent.

规格	价格	库存
5 mg	￥2280	In stock
10 mg	￥3680	In stock
25 mg	￥5980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Vutiglabridin (HSG4112) is a synthetic structural analog of glabridin and insulin sensitizer, novel anti-obesity agent.
HSG4112 dose-dependently reduces body weight and normalizes obesity-related parameters in HFD-induced obese mice orally administered with 10, 30, or 100 mg/kg dose for 6 weeks.
HSG4112 enhances energy expenditure in HFD-induced obese mice.
HSG4112 regulates metabolic gene expression toward increased energy expenditure in liver and muscles.
HSG4112 ameliorates fatty liver in HFD-induced obese mice orally administered with 100 mg/kg dose for 6 weeks

物理化学性质&存储条件

分子量	354.446
分子式	C22H26O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-(8,8-dimethyl-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromen-3-yl)-5-ethoxyphenol

参考文献

1. Choi LS, et al. Int J Obes (Lond). 2021 Jan;45(1):130-142.

2. Bae IY, et al. Pharmaceutics. 2020 Feb 3;12(2):127.

Vutiglabridin (HSG4112)

生物&药学活性

物理化学性质&存储条件

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Vutiglabridin (HSG4112)

生物&药学活性

物理化学性质&存储条件

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