Vorolanib | VEGFR/PDGFR inhibitor | Probechem Biochemicals

Chemical Structure : Vorolanib

CAS No.: 1013920-15-4

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Vorolanib (CM-082, X-82, CM082)

货号: PC-61437Not For Human Use, Lab Use Only.

Vorolanib (CM-082) is an orally available, small molecule dual VEGFR/PDGFR kinase inhibitor with antiangiogenic and antineoplastic activities.

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10 mg	￥3680	In stock
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生物&药学活性

Vorolanib (CM-082) is an orally available, small molecule dual VEGFR/PDGFR kinase inhibitor with antiangiogenic and antineoplastic activities.
Vorolanib (CM-082) inhibits tumor angiogenesis and tumor cell proliferation, and induces tumor cell death.
Vorolanib (CM-082) has been shown to reduce tissue toxicity by 95 percent compared with first-generation kinase inhibitors.

物理化学性质&存储条件

分子量	439.4914
分子式	C23H26FN5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S,Z)-N-(1-(dimethylcarbamoyl)pyrrolidin-3-yl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

参考文献

1. Jackson TL, et al. JAMA Ophthalmol. 2017 Jul 1;135(7):761-767.

2. Hussain RM, et al. Expert Opin Emerg Drugs. 2017 Sep;22(3):235-246.

Vorolanib (CM-082, X-82, CM082)

生物&药学活性

物理化学性质&存储条件

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Vorolanib (CM-082, X-82, CM082)

生物&药学活性

物理化学性质&存储条件

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