Chemical Structure : Vopratelimab
货号: PC-38868Not For Human Use, Lab Use Only.
Vopratelimab (JTX-2011) is an agonist monoclonal antibody that binds to and activates ICOS, the Inducible T cell CO-Stimulator, a protein on the surface of certain T cells commonly found in many solid tumors.
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Vopratelimab (JTX-2011) is an agonist monoclonal antibody that binds to and activates ICOS, the Inducible T cell CO-Stimulator, a protein on the surface of certain T cells commonly found in many solid tumors.
Vopratelimab (JTX-2011) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity.
Isotype: IgG1-kappa.
Anti-[human ICOS (Inducible T-cell COStimulator, CD278)], human monoclonal antibody.
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外观性状 | Solid | |
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Solubility |
10 mM in DMSO |
1. Amanda Hanson, et al. PLoS One. 2020 Sep 24;15(9):e0239595.
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