Volixibat potassium |CAS:1431935-92-0 Probechem Biochemicals

Chemical Structure : Volixibat potassium

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Volixibat potassium (SHP-626;SAR-548304;LUM-002)

货号: PC-61419Not For Human Use, Lab Use Only.

A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH)..

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1 g		Get quote

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生物&药学活性

A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).

Steatohepatitis

Phase 2 Clinical

物理化学性质&存储条件

分子量	844.045
分子式	C38H50KN3O12S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((2R,3R,4S,5R,6R)-4-(benzyloxy)-6-(3-(3-((3S,4R,5R)-3-butyl-7-(dimethylamino)-3-ethyl-4-hydroxy-1,1-dioxido-2,3,4,5-tetrahydrobenzo[b]thiepin-5-yl)phenyl)ureido)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)methyl hydrogen sulfate, potassium salt

参考文献

1. Siebers N, et al. Eur J Drug Metab Pharmacokinet. 2017 Jul 12. doi: 10.1007/s13318-017-0429-7.

2. Tiessen RG, et al. BMC Gastroenterol. 2018 Jan 5;18(1):3.

Volixibat potassium (SHP-626;SAR-548304;LUM-002)

生物&药学活性

物理化学性质&存储条件

参考文献

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Volixibat potassium (SHP-626;SAR-548304;LUM-002)

生物&药学活性

物理化学性质&存储条件

参考文献

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