Volixibat (SHP626, SAR548304, LUM002)

Chemical Structure : Volixibat

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货号: PC-61418Not For Human Use, Lab Use Only.

Volixibat (SHP626, SAR548304, LUM002) is a highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Volixibat (SHP626, SAR548304, LUM002) is a highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).

物理化学性质&存储条件

分子量	805.96
分子式	C38H51N3O12S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[3-[(3S,4R,5R)-3-Butyl-7-(dimethylamino)-3-ethyl-2,3,4,5-tetrahydro-4-hydroxy-1,1-dioxido-1-benzothiepin-5-yl]phenyl]-N'-[3-O-(phenylmethyl)-6-O-sulfo-β-D-glucopyranosyl]urea

参考文献

1. Siebers N, et al. Eur J Drug Metab Pharmacokinet. 2017 Jul 12. doi: 10.1007/s13318-017-0429-7.

2. Tiessen RG, et al. BMC Gastroenterol. 2018 Jan 5;18(1):3.