Vipadenant |CAS:442908-10-3 Probechem Biochemicals

Chemical Structure : Vipadenant

CAS No.: 442908-10-3

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Vipadenant (BIIB-014;BIIB 014;BIIB014)

货号: PC-42717Not For Human Use, Lab Use Only.

Vipadenant (BIIB014) is a potent and selective A2A adenosine receptor antagonist with Ki of 1.3 nM.

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1880	In stock
25 mg	￥2980	In stock
50 mg	￥4780	In stock
100 mg		Get quote

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生物&药学活性

Vipadenant (BIIB014) is a potent and selective A2A adenosine receptor antagonist with Ki of 1.3 nM.
Vipadenant (BIIB014) displays 50-fold selectivity over A1 and A2B, and no activity against A3, P450 isoforms and hERG.
Vipadenant (BIIB014) shows excellent preclinical pharmacokinetics, and demonstrates strong oral activity in commonly used models of Parkinson's disease.

物理化学性质&存储条件

分子量	321.3366
分子式	C16H15N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 31 mg/mL
Chemical Name/SMILES	3H-1,2,3-Triazolo[4,5-d]pyrimidin-5-amine, 3-[(4-amino-3-methylphenyl)methyl]-7-(2-furanyl)-

参考文献

1. Gillespie RJ, et al. J Med Chem. 2009 Jan 8;52(1):33-47.

2. Pinna A. Expert Opin Investig Drugs. 2009 Nov;18(11):1619-31.

3. Brooks DJ, et al. Clin Neuropharmacol. 2010 Mar-Apr;33(2):55-60.

Vipadenant (BIIB-014;BIIB 014;BIIB014)

生物&药学活性

物理化学性质&存储条件

参考文献

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Vipadenant (BIIB-014;BIIB 014;BIIB014)

生物&药学活性

物理化学性质&存储条件

参考文献

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