Chemical Structure : Vicadrostat
货号: PC-24049Not For Human Use, Lab Use Only.
Vicadrostat (BI 690517) is a potent, highly selective aldosterone synthase (AS) inhibitor with IC50 of 48 nM, 250-fold selectivity for aldosterone synthase compared with cortisol synthase.
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Vicadrostat (BI 690517) is a potent, highly selective aldosterone synthase (AS, CYP11B2, steroid 18-hydroxylase)) inhibitor with IC50 of 48 nM, 250-fold selectivity for aldosterone synthase compared with cortisol synthase.
分子量 | 317.73 | |
分子式 | C15H12ClN3O3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Katherine R Tuttle, et al. Lancet. 2024 Jan 27;403(10424):379-390.
2. Patent WO2016014736.
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