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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-Vernakalant hydrochloride
Vernakalant hydrochloride

Chemical Structure : Vernakalant hydrochloride

CAS No.: 748810-28-8

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Vernakalant hydrochloride (RSD1235 hydrochloride)

货号: PC-23682Not For Human Use, Lab Use Only.

Vernakalant (RSD1235) is an atrial-selective antifibrillatory agent and mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker, inhibits wild-type and mutant Kv1.5 channels.

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2 mg ￥780 In stock
5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3480 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Vernakalant (RSD1235) is an atrial-selective antifibrillatory agent and mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker, inhibits wild-type and mutant Kv1.5 channels.

物理化学性质&存储条件

分子量 385.93
分子式 C20H32ClNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-1-((1R,2R)-2-(3,4-Dimethoxyphenethoxy)cyclohexyl)pyrrolidin-3-ol hydrochloride

参考文献

1. Dorian P, et al. J Cardiovasc Pharmacol. 2007 Jul;50(1):35-40.

2. Eldstrom J, et al. Mol Pharmacol. 2007 Dec;72(6):1522-34.

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