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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Cathepsin-Verducatib
Verducatib

Chemical Structure : Verducatib

CAS No.: 1887236-33-0

Verducatib

货号: PC-24193Not For Human Use, Lab Use Only.

Verducatib is a potent, selective inhibitor of cathepsin C (CatC) with IC50 of 1.1 nM, patent WO2016038007 A1 (compound II).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Verducatib is a potent, selective inhibitor of cathepsin C (CatC) with IC50 of 1.1 nM, patent WO2016038007 A1 (compound II).

物理化学性质&存储条件

分子量 530.64
分子式 C31H35FN4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,3S,4S)-N-((S)-1-cyano-2-(2-fluoro-4-(1'-(oxetan-3-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-6-yl)phenyl)ethyl)-2-azabicyclo[2.2.1]heptane-3-carboxamide

参考文献

1. Patent WO2016038007 A1 (compound II).

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