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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Complement System-Vemircopan
Vemircopan

Chemical Structure : Vemircopan

CAS No.: 2086178-00-7

Vemircopan (ALXN2050, ACH 5228, ACH 0145228)

货号: PC-38358Not For Human Use, Lab Use Only.

Vemircopan (ALXN2050, ACH 5228) is a second generation, orally active complement factor D inhibitor, has the potential to decrease disease symptoms and increase strength in generalized myasthenia gravis (gMG).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Vemircopan (ALXN2050, ACH 5228) is a second generation, orally active complement factor D inhibitor, has the potential to decrease disease symptoms and increase strength in generalized myasthenia gravis (gMG).

    物理化学性质&存储条件

    分子量 602.48
    分子式 C29H28BrN7O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (1R,3S,5R)-2-(2-(3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromo-3-methylpyridin-2-yl)-5-methyl-2-azabicyclo[3.1.0]hexane-3-carboxamide

    参考文献

    1. Pantent WO2014145025A2.

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