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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HCV-Velpatasvir
Velpatasvir

Chemical Structure : Velpatasvir

CAS No.: 1377049-84-7

Velpatasvir (GS-5816;GS 5816;GS5816)

货号: PC-43099Not For Human Use, Lab Use Only.

Velpatasvir (GS-5816) is a second generation, pan-genotypic inhibitor of HCV NS5A, demonstrates a high barrier to resistance in HCV replicon assays..

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50 mg ¥1280 In stock
100 mg ¥1980 In stock
200 mg ¥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Velpatasvir (GS-5816) is a second generation, pan-genotypic inhibitor of HCV NS5A, demonstrates a high barrier to resistance in HCV replicon assays.

物理化学性质&存储条件

分子量 883.0018
分子式 C49H54N8O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 146.66 mg/mL (Need ultrasonic and warming)

Chemical Name/SMILES

Carbamic acid, N-[(1R)-2-[(2S,4S)-2-[5-[1,11-dihydro-2-[(2S,5S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-5-methyl-2-pyrrolidinyl][2]benzopyrano[4',3':6,7]naphth[1,2-d]imidazol-9-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)-1-pyrrolidinyl]-2-oxo-

参考文献

1. Curry MP, et al. N Engl J Med. 2015 Dec 31;373(27):2618-28.

2. Gane EJ, et al. Gastroenterology. 2016 Sep;151(3):448-456.e1.

3. Nakamoto S, et al. World J Gastroenterol. 2014 Mar 21;20(11):2902-12.

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