Chemical Structure : Varlilumab
CAS No.: 1393344-72-3
货号: PC-Ab1082Not For Human Use, Lab Use Only.
Varlilumab (CDX-1127) is a novel, first-in-class fully human IgG1 kappa anti-CD27 monoclonal antibody that acts as an agonist of CD27 by interaction with the CD70-binding site. Varlilumab (CDX-1127) stimulates the CD27 pathway, which results in T-cell activation and antitumor activity in tumor models..
规格 | 价格 | 库存 | 数量 |
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1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Varlilumab (CDX-1127) is a novel, first-in-class fully human IgG1 kappa anti-CD27 monoclonal antibody that acts as an agonist of CD27 by interaction with the CD70-binding site. Varlilumab (CDX-1127) stimulates the CD27 pathway, which results in T-cell activation and antitumor activity in tumor models.
分子量 | ||
分子式 | Human IgG4P-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Varlilumab; CDX-1127; CDX1127; Anti-human TNFRSF7; 1F5; 1393344-72-3; anti human CD27; Cluster of differentiation 27 |
1. 1, Ansell SM, et al. Blood Adv. 2020 May 12;4(9):1917-1926. 2, Burris HA, et al. J Clin Oncol. 2017 Jun 20;35(18):2028-2036. 3, Ramakrishna V, et al. J Immunother Cancer. 2015 Aug 18;3:37. 4, Turaj AH, et al. Cancer Cell. 2017 Dec 11;32(6):777-791.e6.
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