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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-nAChR-Varenicline
Varenicline

Chemical Structure : Varenicline

CAS No.: 249296-44-4

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Varenicline (CP 526555)

货号: PC-26759Not For Human Use, Lab Use Only.

Varenicline (CP 526555) is a potent, orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR) with IC50 of 250 nM, is also a partial agonist of α6β2 nAChR and a full agonist of α7β2 nAChR.

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25 mg ￥1280 In stock
50 mg ￥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Varenicline (CP 526555) is a potent, orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR) with IC50 of 250 nM, is also a partial agonist of α6β2 nAChR and a full agonist of α7β2 nAChR.

物理化学性质&存储条件

分子量 211.27
分子式 C13H13N3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline

参考文献

1. Koegelenberg CF, et al. JAMA. 2014 Jul;312(2):155-61.

2. Koga M, et al. Toxicology. 2017;390:1-9.

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