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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Enterovirus-Vapendavir
Vapendavir

Chemical Structure : Vapendavir

CAS No.: 439085-51-5

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Vapendavir (BTA798, BTA-798)

货号: PC-63340Not For Human Use, Lab Use Only.

Vapendavir (BTA798) is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Vapendavir (BTA798) is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.
Vapendavir (BTA798) efficiently inhibits the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C.
Vapendavir (BTA798) is currently under clinical study for the treatment of rhinovirus infections.

物理化学性质&存储条件

分子量 382.464
分子式 C21H26N4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-ethoxy-6-[2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethoxy]-1,2-benzoxazole

参考文献

1. Tijsma A, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2.

2. Sun L, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.

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