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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-CFTR-Vanzacaftor
Vanzacaftor

Chemical Structure : Vanzacaftor

CAS No.: 2374124-49-7

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Vanzacaftor (VX-121, VX121)

货号: PC-73453Not For Human Use, Lab Use Only.

Vanzacaftor (VX-121) is a potent, selective cystic fibrosis transmembrane regulator (CFTR) corrector, with potential for treatment of cystic fibrosis.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Vanzacaftor (VX-121) is a potent, selective cystic fibrosis transmembrane regulator (CFTR) corrector, with potential for treatment of cystic fibrosis.

    物理化学性质&存储条件

    分子量 617.76
    分子式 C32H39N7O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    13H-17,20-Methano-8,12-nitrilo-12H-pyrido[3,2-d][1,2,6,13]thiatriazacyclooctadecin-5(6H)-one, 2-[3-(2-dispiro[2.0.2.1]hept-7-ylethoxy)-1H-pyrazol-1-yl]-14,15,16,17,18,19-hexahydro-19,19-dimethyl-, 7,7-dioxide, (17S)-

    参考文献

    1. Aaron Kolski-Andreaco, et al. J Clin Invest. 2024 Jul 2:e176328.

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