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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P-glycoprotein (P-gp)-Valspodar
Valspodar

Chemical Structure : Valspodar

CAS No.: 121584-18-7

Valspodar (PSC833, SDZ PSC-833)

货号: PC-45207Not For Human Use, Lab Use Only.

Valspodar (PSC-833) is a highly potent multidrug-resistance modifier that acts as a P-glycoprotein MDR1 inhibitor, exhibits effectivity at preventing cancer cell resistance to chemotherapeutics.

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5 mg ¥3580 In stock
10 mg ¥5580 In stock
25 mg ¥8980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Valspodar (PSC-833) is a highly potent multidrug-resistance modifier that acts as a P-glycoprotein MDR1 inhibitor, exhibits effectivity at preventing cancer cell resistance to chemotherapeutics.

物理化学性质&存储条件

分子量 1214.622
分子式 C63H111N11O12
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 12 mg/mL

Chemical Name/SMILES

Cyclosporin A, 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-

参考文献

1. Boesch D, et al. Cancer Res. 1991 Aug 15;51(16):4226-33.

2. Ehrlich PH, et al. Anticancer Res. 1997 Jan-Feb;17(1A):129-33.

3. Hu XF, et al. Clin Cancer Res. 1996 Apr;2(4):713-20.

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