VX-984 |CAS:1562396-65-9 Probechem Biochemicals

Chemical Structure : VX-984

CAS No.: 1562396-65-9

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VX-984 (M9831;VX984)

货号: PC-61971Not For Human Use, Lab Use Only.

VX-984 (M9831) is a potent, selective inhibitor of DNA-PK with IC50 of 88 nM for inhibition of DNA-PKcs autophosphorylation (Ser2056) in A549 lung cancer cells, with good selectivity versus other PI3K family members.

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2 mg	￥3580	In stock
5 mg	￥5580	In stock
10 mg	￥9580	In stock
25 mg		Get quote
100 mg		Get quote

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生物&药学活性

VX-984 (M9831) is a potent, selective inhibitor of DNA-PK with IC50 of 88 nM for inhibition of DNA-PKcs autophosphorylation (Ser2056) in A549 lung cancer cells, with good selectivity versus other PI3K family members.

物理化学性质&存储条件

分子量	401.4702
分子式	C22H19D2N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-[(1S)-1-Methyl-2-[(2'-methyl[4,5'-bipyrimidin]-6-yl-4',6'-d2)amino]ethyl]-4-quinolinecarboxamide

参考文献

1. Harnor SJ, et al. ChemMedChem. 2017 Jun 21;12(12):895-900.

2. D. Boucher, R, et al. AACR; Abstract No. 3716.

VX-984 (M9831;VX984)

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物理化学性质&存储条件

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VX-984 (M9831;VX984)

生物&药学活性

物理化学性质&存储条件

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