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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P-glycoprotein (P-gp)-VX-853
VX-853

Chemical Structure : VX-853

CAS No.: 179033-51-3

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VX-853 (Timcodar, VX853)

货号: PC-21827Not For Human Use, Lab Use Only.

Timcodar (VX-853) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), directly blockes EtBr efflux in S. aureus.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Timcodar (VX-853) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), directly blockes EtBr efflux in S. aureus.

物理化学性质&存储条件

分子量 749.31
分子式 C43H45ClN4O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S)-N-benzyl-3-(4-chlorophenyl)-N-(1,5-dipyridin-4-ylpentan-3-yl)-2-[methyl-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]amino]propanamide

参考文献

1. Mullin S, et al. Antimicrob Agents Chemother. 2004 Nov;48(11):4171-6.

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