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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P-glycoprotein (P-gp)-VX-710
VX-710

Chemical Structure : VX-710

CAS No.: 159997-94-1

VX-710 (Biricodar, VX710)

货号: PC-21826Not For Human Use, Lab Use Only.

Biricodar (VX-710) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), modulates Pgp, MRP-1, and BCRP(R482), enhances chemosensitivity in resistant cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Biricodar (VX-710) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), modulates Pgp, MRP-1, and BCRP(R482), enhances chemosensitivity in resistant cells.

物理化学性质&存储条件

分子量 603.72
分子式 C34H41N3O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,7-dipyridin-3-ylheptan-4-yl (2S)-1-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate

参考文献

1. Germann UA, et al. Anticancer Drugs. 1997 Feb;8(2):125-40.

2. Minderman H, et al. Clin Cancer Res. 2004 Mar 1;10(5):1826-34.

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