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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-VUF11403
VUF11403

Chemical Structure : VUF11403

CAS No.: 1378524-61-8

VUF11403 (VUF-11403, VUF 11403)

货号: PC-60260Not For Human Use, Lab Use Only.

VUF11403 is a potent CXCR7 (ACKR3) agonist with pKi of 8.1 (hCXCR7), induces recruitment of β-arrestin2 and subsequent internalization of CXCR7.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VUF11403 is a potent CXCR7 (ACKR3) agonist with pKi of 8.1 (hCXCR7), induces recruitment of β-arrestin2 and subsequent internalization of CXCR7.

    物理化学性质&存储条件

    分子量 440.56
    分子式 C26H33FN2O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-N-(3-(2-Fluorophenyl)-2-methylallyl)-3,4-dimethoxy-N-(2-(1-methylpyrrolidin-2-yl)ethyl)benzamide

    参考文献

    1. Wijtmans M, et al. Eur J Med Chem. 2012 May;51:184-92.

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