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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-VUF11222
VUF11222

Chemical Structure : VUF11222

CAS No.: 1414376-84-3

VUF11222 (VUF 11222)

货号: PC-21816Not For Human Use, Lab Use Only.

VUF11222 is a potent, selective and nonpeptidomimetic CXCR3 agonist with binding pKi of 7.2, and pEC50 of 6.1 in [35S]GTPγS functional assays.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VUF11222 is a potent, selective and nonpeptidomimetic CXCR3 agonist with binding pKi of 7.2, and pEC50 of 6.1 in [35S]GTPγS functional assays.

物理化学性质&存储条件

分子量 552.34
分子式 C25H31BrIN
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(2'-Bromobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium Iodide

参考文献

1. Wijtmans M, et al. J Med Chem. 2012 Dec 13;55(23):10572-83.

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