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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-VUF11207 fumarate
VUF11207 fumarate

Chemical Structure : VUF11207 fumarate

CAS No.: 1785665-61-3

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VUF11207 fumarate (VUF-11207, VUF 11207)

货号: PC-60259Not For Human Use, Lab Use Only.

VUF11207 fumarate is a potent CXCR7 (ACKR3) agonist with EC50 of 1.6 nM, inducse recruitment of β-arrestin2 and subsequent internalization of CXCR7 in cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

VUF11207 fumarate is a potent CXCR7 (ACKR3) agonist with EC50 of 1.6 nM, inducse recruitment of β-arrestin2 and subsequent internalization of CXCR7 in cells.

物理化学性质&存储条件

分子量 586.66
分子式 C31H39FN2O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fumarate

参考文献

1. Wijtmans M, et al. Eur J Med Chem. 2012 May;51:184-92.

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