欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-VU714 oxalate
VU714 oxalate

Chemical Structure : VU714 oxalate

CAS No.: 474625-52-0

加入收藏

VU714 oxalate (VU-714 oxalate, VU 714 oxalate)

货号: PC-60574Not For Human Use, Lab Use Only.

VU714 oxalate is a potent inwardly rectifying K+ channel Kir7.1 inhibitor with IC50 of 5.6 uM in T1+ flux assays.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VU714 oxalate is a potent inwardly rectifying K+ channel Kir7.1 inhibitor with IC50 of 5.6 uM in T1+ flux assays.
    VU714 oxalate inhibits other Kir channels with a rank order potency of Kir4.1 (IC50=13 µM) > Kir1.1 (IC50=16 µM) > Kir6.2/SUR1 (IC50=30 µM) > Kir2.1, Kir2.2, Kir2.3, Kir3.1/3.2 (IC50 > 30 µM).

    物理化学性质&存储条件

    分子量 456.92
    分子式 C24H25ClN2O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    7-((4-benzylpiperidin-1-yl)methyl)-5-chloroquinolin-8-ol oxalate

    参考文献

    1. Kharade SV, et al. Mol Pharmacol. 2017 Sep;92(3):338-346.

    2. Swale DR, et al. ACS Chem Neurosci. 2016 Jul 20;7(7):1013-23.

    备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    联系我们 sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    询单

    • *产品名称:
    • *姓名:
    • *邮箱:
    • *公司名称:
    • *询单数量:
    • *国籍:
    • 询单信息: