VU6046980 | mGlu7 PAM | Probechem Biochemicals

Chemical Structure : VU6046980

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货号: PC-49586Not For Human Use, Lab Use Only.

VU6046980 is a potent, selective and in vivo active mGlu7 positive allosteric modulator (PAM) with EC50 of 0.15 uM (rat mGlu7).

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VU6046980 is a potent, selective and in vivo active mGlu7 positive allosteric modulator (PAM) with EC50 of 0.15 uM (rat mGlu7).

分子量	409.397
分子式	C21H17F2N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-6-fluoro-4-(10-fluoro-1,2,4a,5-tetrahydrobenzo[b]pyrazino[1,2-d][1,4]oxazin-3(4H)-yl)-8-methoxycinnoline-3-carbonitrile

1. Jacob J Kalbfleisch, et al. Bioorg Med Chem Lett. 2022 Dec 15;80:129106