欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-GPCR-mGluR-VU6010572
VU6010572

Chemical Structure : VU6010572

CAS No.: 2126784-39-0

加入收藏

VU6010572 (VU-6010572)

货号: PC-60937Not For Human Use, Lab Use Only.

VU6010572 is a potent and selective, CNS penetrant mGlu3 negative allosteric modulator with IC50 of 245 nM.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VU6010572 is a potent and selective, CNS penetrant mGlu3 negative allosteric modulator with IC50 of 245 nM.
    VU6010572 show no inhibition for mGlu2 (IC50>30 uM).
    VU6010572 displays improved physiochemical properties and in vivo efficacy in a mouse tail suspension test (MED = 3 mg/kg i.p.).

    物理化学性质&存储条件

    分子量 339.366
    分子式 C20H18FNO3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-1-(4-fluorophenyl)-4-(2-phenoxypropoxy)pyridin-2(1H)-one

    参考文献

    1. Engers JL, et al. ACS Med Chem Lett. 2017 Aug 15;8(9):925-930.

    备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    联系我们 sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    询单

    • *产品名称:
    • *姓名:
    • *邮箱:
    • *公司名称:
    • *询单数量:
    • *国籍:
    • 询单信息: