欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-GPCR-mGluR-VU6005649
VU6005649

Chemical Structure : VU6005649

CAS No.: 2137047-43-7

加入收藏

VU6005649 (VU 6005649;VU-6005649)

货号: PC-60162Not For Human Use, Lab Use Only.

VU6005649 is a potent, CNS penetrant, dual mGlu7/8 positive allosteric modulator with EC50 of 0.65/2.6 uM, respectively.

规格 价格 库存 数量
10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3580 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

VU6005649 is a potent, CNS penetrant, dual mGlu7/8 positive allosteric modulator with EC50 of 0.65/2.6 uM, respectively.
VU6005649 displays no activity for mGlu4 (EC50>10 uM).
VU6005649 shows modest but significant pro-cognitive effects on associative learning in wild type mice.

物理化学性质&存储条件

分子量 357.284
分子式 C16H12F5N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(2,3-difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

参考文献

1. Abe M, et al. ACS Med Chem Lett. 2017 Sep 1;8(10):1110-1115.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: