欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-VU591
VU591

Chemical Structure : VU591

CAS No.: 1222810-74-3

加入收藏

VU591 (VU-591, VU 591)

货号: PC-60571Not For Human Use, Lab Use Only.

VU591 is a potent, selective renal outer medullary potassium channel (ROMK, Kir1.1) inhibitor with IC50 of 0.24 uM in T1+ flux assays.

规格 价格 库存 数量
5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3580 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

VU591 is a potent, selective renal outer medullary potassium channel (ROMK, Kir1.1) inhibitor with IC50 of 0.24 uM in T1+ flux assays.
VU591 has no effect on Kir7.1 at 10 uM, does not inhibit Kir2.1, Kir2.3 and Kir4.1, 150-fold selectivity over Kir6.2/SUR1.
VU591 blocks the intracellular pore of the channel and is a useful probe to explore the viability of ROMK as a diuretic target.

物理化学性质&存储条件

分子量 368.309
分子式 C16H12N6O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,2'-(oxybis(methylene))bis(6-nitro-1H-benzo[d]imidazole)

参考文献

1. Bhave G, et al. Mol Pharmacol. 2011 Jan;79(1):42-50.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: