VU534 | NAPE-PLD activator | Probechem Biochemicals

Chemical Structure : VU534

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VU534 (VU 534)

货号: PC-20921Not For Human Use, Lab Use Only.

VU534 is a small molecule activator of N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) with EC50 of 0.3 uM, enhances efferocytosis by macrophages.

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生物&药学活性

VU534 is a small molecule activator of N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) with EC50 of 0.3 uM, enhances efferocytosis by macrophages.
VU534 (10 uM) increases the NAPE-PLD activity of RAW264.7 macrophages.
VU534 enhances efferocytosis in a NAPE-PLD-dependent manner in bone-marrow derived macrophages (BMDM).

物理化学性质&存储条件

分子量	447.54
分子式	C21H22FN3O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(C1CCN(S(=O)(C2=CC=C(F)C=C2)=O)CC1)NC3=NC4=CC(C)=CC(C)=C4S3

参考文献

1. Jonah E Zarrow, et al. bioRxiv. 2023 Feb 28;2023.01.25.525554.

VU534 (VU 534)

生物&药学活性

物理化学性质&存储条件

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VU534 (VU 534)

生物&药学活性

物理化学性质&存储条件

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