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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-VU0948578
VU0948578

Chemical Structure : VU0948578

CAS No.:

VU0948578 (VU 0948578)

货号: PC-22563Not For Human Use, Lab Use Only.

VU0948578 is a potent, selective inhibitor of WT, A934T, and G288S SLACK channel (KCNT1, KNa1.1) with IC50 of 0.70, 0.59, 0.71 µM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VU0948578 is a potent, selective inhibitor of WT, A934T, and G288S SLACK channel (KCNT1, KNa1.1) with IC50 of 0.70, 0.59, 0.71 µM respectively.

物理化学性质&存储条件

分子量 479.56
分子式 C26H30FN5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-(butyl(4-fluorobenzyl)amino)-1-(3-methoxybenzyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

参考文献

1. Alshaima'a M Qunies, et al. Molecules. 2024 May 22;29(11):2437.

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