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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-VU0935685
VU0935685

Chemical Structure : VU0935685

CAS No.:

VU0935685 (VU 0935685)

货号: PC-21229Not For Human Use, Lab Use Only.

VU0935685 is a potent, selective inhibitor of SLACK potassium channels with IC50 of 0.32 uM in in whole-cell, voltage-clamp electrophysiology (EP) assays, demonstrates selectivity versus hERG.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VU0935685 is a potent, selective inhibitor of SLACK potassium channels with IC50 of 0.32 uM in in whole-cell, voltage-clamp electrophysiology (EP) assays, demonstrates selectivity versus hERG.

物理化学性质&存储条件

分子量 424.45
分子式 C21H17FN4O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(4-Fluorophenyl)-5-(1-((2-methylquinolin-8-yl)sulfonyl)azetidin-3-yl)-1,2,4-oxadiazole

参考文献

1. Qunies AM, et al. Bioorg Med Chem. 2023 Sep 30;95:117487.

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