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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-VU0521426
VU0521426

Chemical Structure : VU0521426

CAS No.: 1396886-76-2

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VU0521426 (VU426)

货号: PC-26855Not For Human Use, Lab Use Only.

VU0521426 (VU426) is a potent, selective Kv3.1 channel inhibitor with IC50 of 4.3 uM, suppresses Kv3.1 activity413through a state-dependent mechanism consistent with stabilization of non-conducting channel states.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VU0521426 (VU426) is a potent, selective Kv3.1 channel inhibitor with IC50 of 4.3 uM, suppresses Kv3.1 activity413through a state-dependent mechanism consistent with stabilization of non-conducting channel states.

物理化学性质&存储条件

分子量 421.96
分子式 C19H20ClN3O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-((5-chlorothiophen-2-yl)sulfonyl)-4-((2-phenyl-1H-imidazol-1-yl)methyl)piperidine

参考文献

1. Rahul U Chandrappa, et al. Am J Physiol Cell Physiol. 2026 May 15.

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