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首页-小分子抑制剂&激动剂-GPCR-mGluR-VU0410425
VU0410425

Chemical Structure : VU0410425

CAS No.: 1341167-72-3

VU0410425 (VU 0410425)

货号: PC-62956Not For Human Use, Lab Use Only.

VU0410425 is a potent, selective negative allosteric modulator of rat mGluR1 with IC50 of 140 nM, inactive at human mGluR1 (IC50>30 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VU0410425 is a potent, selective negative allosteric modulator of rat mGluR1 with IC50 of 140 nM, inactive at human mGluR1 (IC50>30 uM).

    物理化学性质&存储条件

    分子量 369.805
    分子式 C19H16ClN3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-[3-Chloro-4-[(1S,5R)-6,6-dimethyl-2,4-dioxo-3-azabicyclo[3.1.0]hexan-3-yl]phenyl]pyridine-2-carboxamide

    参考文献

    1. Cho HP, et al. ACS Chem Neurosci. 2014 Jul 16;5(7):597-610.

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