VU0405601 |CAS:712325-30-9 Probechem Biochemicals

Chemical Structure : VU0405601

加入收藏

VU0405601 (VU 0405601;VU-0405601)

货号: PC-60841Not For Human Use, Lab Use Only.

VU0405601 is a potent Kv11.1 (hERG) channel allosteric modulator that protects cardiac tissue from hERG-related drug-induced arrhythmias.

规格	价格	库存	数量
5 mg		Get quote
10 mg		Get quote
25 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

VU0405601 is a potent Kv11.1 (hERG) channel allosteric modulator that protects cardiac tissue from hERG-related drug-induced arrhythmias.
VU0405601 increases the IC(50) of dofetilide from 38.7 to 76.3 nM, mitigates the effects of hERG blockers from the extracellular aspect primarily by reducing inactivation.
VU0405601 reduces the sensitivity of hERG to inhibitors.

物理化学性质&存储条件

分子量	357.207
分子式	C17H13BrN2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((1-Bromonaphthalen-2-yl)oxy)-N-(pyridin-3-yl)acetamide

参考文献

1. Potet F, et al. J Biol Chem. 2012 Nov 16;287(47):39613-25.

2. Yu Z, et al. Circ Arrhythm Electrophysiol. 2016 Apr;9(4):e003439.

VU0405601 (VU 0405601;VU-0405601)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

VU0405601 (VU 0405601;VU-0405601)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.