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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-VU0364739
VU0364739

Chemical Structure : VU0364739

CAS No.: 1244639-78-8

VU0364739 (VU 0364739)

货号: PC-49071Not For Human Use, Lab Use Only.

VU0364739 is a potent, selective allosteric inhibitor of phospholipase D2 (PLD2) with cellular IC50 of 20 nM, >75-fold selectivity over PLD1.

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10 mg ¥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

VU0364739 is a potent, selective allosteric inhibitor of phospholipase D2 (PLD2) with cellular IC50 of 20 nM, >75-fold selectivity over PLD1.

物理化学性质&存储条件

分子量 446.526
分子式 C26H27FN4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[2-[1-(3-Fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-2-naphthalenecarboxamide

参考文献

1. Sarah A. Scott, et al. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.2012 Apr 5 [updated 2013 Mar 14].

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