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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-VU0285655-1
VU0285655-1

Chemical Structure : VU0285655-1

CAS No.: 1158347-73-9

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VU0285655-1 (BML280, VU0285655)

货号: PC-72955Not For Human Use, Lab Use Only.

VU0285655-1 (BML280) is a potent, selective inhibitor of PLD2, prevents caspase-3 cleavage and reduction in cell viability induced by high glucose, induces autophagy in colorectal cancer cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

VU0285655-1 (BML280) is a potent, selective inhibitor of PLD2, prevents caspase-3 cleavage and reduction in cell viability induced by high glucose, induces autophagy in colorectal cancer cells.

物理化学性质&存储条件

分子量 465.98
分子式 C25H28ClN5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-3-carboxamide hydrochloride

参考文献

1. Burkhardt U, et al. Eur J Pharmacol. 2015 Aug 15;761:398-404.

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