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首页-小分子抑制剂&激动剂-GPCR-mGluR-VU0155094
VU0155094

Chemical Structure : VU0155094

CAS No.: 731006-86-3

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VU0155094 (ML397)

货号: PC-62130Not For Human Use, Lab Use Only.

VU0155094 (ML397) is a potent, selective pan-Group III mGlu positive allosteric modulator with IC50 of 3.43/1.5/0.93 uM for mGlu8/7/4, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VU0155094 (ML397) is a potent, selective pan-Group III mGlu positive allosteric modulator with IC50 of 3.43/1.5/0.93 uM for mGlu8/7/4, respectively.
    VU0155094 displays >30-fold selectivity over groups I and II mGlus (mGlu1/2/3/5/6).

    物理化学性质&存储条件

    分子量 436.526
    分子式 C24H24N2O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    Methyl 4-[3-[2-(4-acetamidophenyl)sulfanylacetyl]-2,5-dimethylpyrrol-1-yl]benzoate

    参考文献

    1. Jalan-Sakrikar N, et al. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37.

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