欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-VU0155069
VU0155069

Chemical Structure : VU0155069

CAS No.: 1130067-06-9

加入收藏

VU0155069 (VU 0155069, CAY10593)

货号: PC-63190Not For Human Use, Lab Use Only.

VU0155069 is a potent, selective phospholipase D1 (PLD1) inhibitor with IC50 of 46 nM, 20-fold selectivity over PLD2 (IC50=933 nM).

规格 价格 库存 数量
10 mg ￥1280 In stock
25 mg ￥1980 In stock
50 mg ￥3280 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

VU0155069 is a potent, selective phospholipase D1 (PLD1) inhibitor with IC50 of 46 nM, 20-fold selectivity over PLD2 (IC50=933 nM).
VU0155069 sensitizes MCF7 and MDA-MB-231 breast cancer cells to doxorubicin-induced cytotoxicity.
VU0155069 suppresses growth of colorectal cancer activated by the Wnt/β-catenin and PI3K signaling pathways.

物理化学性质&存储条件

分子量 462.978
分子式 C26H27ClN4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[(1S)-2-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl]-2-naphthalenecarboxamide

参考文献

1. Scott SA, et al. Nat Chem Biol. 2009 Feb;5(2):108-17.

2. Song HI, et al. Sci Rep. 2016 Nov 22;6:36968.

3. Kang DW, et al. Clin Cancer Res. 2017 Dec 1;23(23):7340-7350.

4. Cheng M, et al. Neoplasia. 2017 Aug;19(8):617-627.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: