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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-VU0038882
VU0038882

Chemical Structure : VU0038882

CAS No.: 429653-28-1

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VU0038882 (VU 0038882)

货号: PC-70355Not For Human Use, Lab Use Only.

VU0038882 is a small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VU0038882 is a small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism.
    VU0038882 prevents the emergence of antibiotic resistance, enhances phagocyte killing, and reduces S. aureus pathogenesis.

    物理化学性质&存储条件

    分子量 276.295
    分子式 C17H12N2O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(3-(furan-2-yl)-1H-pyrazol-5-yl)naphthalen-1-ol

    参考文献

    1. Mike LA, et al. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8206-11.

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