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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ras-VT204
VT204

Chemical Structure : VT204

CAS No.: 2756227-86-6

VT204 (VT-204)

货号: PC-22825Not For Human Use, Lab Use Only.

VT204 is a small molecule inhibitor of KRAS G12C, effectively suppresses cell proliferation in NCI-H358 cells at 8 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VT204 is a small molecule inhibitor of KRAS G12C, effectively suppresses cell proliferation in NCI-H358 cells at 8 uM.

物理化学性质&存储条件

分子量 514.98
分子式 C24H21ClF2N6OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-((2R,5S)-4-(7-(2-amino-7-fluorobenzo[d]thiazol-4-yl)-6-chloro-8-fluoroquinazolin-4-yl)-2,5-dimethylpiperazin-1-yl)prop-2-en-1-one

参考文献

1. Xuechao Yang, et al. Technol Cancer Res Treat. 2024 Jan-Dec:23:15330338241264853.

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